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Epidermal Cysts of the Breast in a Developing Community- Juniper publishers

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International Journal of Cell Science & Molecular Biology Only a few cases of epidermal cysts of the breast have been reported in the literature. The lesion is characterized by a cyst containing keratinous matter and lined by squamous cells . Therefore, a few examples are presented from a developing community on account of the construction of a histopathology data pool that was hailed to be advantageous in epidemiological analysis. Three local cases were found in 2 females and one male between 22 and 60 years; the squamous lining may be partly lost; abscess may be formed with associated cellulitis of the adjoining fat, and foreign body giant cells may appear. Read more please click on:  Full text For more Open access journals please click on Juniper Publishers For more articles please click on Journal of Cell Science & Molecular Biology

Molecular Imaging with Chemokine Receptor4 (Cxcr4) In Breast Cancer- Juniper Publishers

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In this study, CXCR4 siRNA labeled with 99m Tc was used in gene imaging of nude mice for the breast carcinoma. Small interference RNA (siRNA) targeting human CXCR4 was radiolabeled by using the bifunctional chelator HYNIC. Negative control siRNA were synthesized by siRNA targeted to CXCR4 mRNA and radiolabeled by 99m Tc with the bifunctional chelator HYNIC. Animal models of nude mice bearing human breast cancer MDA-MB-231 were established, divided them into three groups, 10 mice in each group. 7.4MBq of 99mTcO4-, 99m Tc- HYNIC(siRNA) and 99m Tc-HYNIC(-siRNA) were separately injected through tail vein to the three groups. Images of these animal modelswere acquired with SPECT, the ratio of T/M was calculated by region of interest (ROI) https://juniperpublishers.com/ijcsmb/IJCSMB.MS.ID.555568.php For more Open access journals please click on Juniper Publishers For more articles please click on Journal of Cell Science & Molecular Biology