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Dedifferentiated Chondrosarcoma of the Larynx: A Case Report and Review of the Literature- Juniper Publishers

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Juniper Publishers- Journal of cell Science Abstract Background: Laryngeal chondrosarcomas are rare, slow-growing, cartilaginous tumors. Dedifferentiated chondrosarcomas, a rare entity of chondrosarcoma, are more aggressive and associated with a more ominous prognosis. Definite diagnosis can be established by incisional biopsy and histopathologic examination. Histopathologic examination reveals a cartilaginous tumor with a malignant spindle cell component. Definitive reatment of dedifferentiated chondrosarcomas of the larynx is total laryngectomy. There have been 14 case reports of laryngeal dedifferentiated chondrosarcoma reported since 1988. The average life expectancy reported is 6 months, and a 5-year survival rate of 10.5%. Case presentation: We present a case of dedifferentiated chondrosarcoma arising in the cricoids cartilage of a male patient, who presented with 3-week history of dyspnea, stridor, dysphonia and intermittent aphonia. As a result, he un...
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Juniper Publishers PubMed Indexed Articles

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Juniper Publishers PubMed Indexed Articles Article Title :   Inter-scan Reproducibility of Cardiovascular Magnetic Resonance Imaging-Derived Myocardial Perfusion Reserve Index in Women with no Obstructive Coronary Artery Disease. Author Information : Louise EJ Thomson and C Noel Bairey Merz1* PubMed ID : PMID:  30976755 PubMed URL : https://www.ncbi.nlm.nih.gov/pubmed/30976755/ Journal Name : Journal of Clinical and Medical Imaging ISSN: 2573-2609 Full Article Link : https://juniperpublishers.com/ctcmi/CTCMI.MS.ID.555587.php Article Title :   What is the Role of Race and Ethnicity in the Development Of Thionamide-Induced Neutropenia? Author Information : Mark R Burge1* PubMed ID : PMID:  30828700 PubMed URL : https://www.ncbi.nlm.nih.gov/pubmed/30828700/ Journal Name : Journal of Endocrinology and Thyroid Research ISSN: 2573-2188 Full Article Link : https://juniperpublishers.com/jetr/    ...
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Cellular migration as a Stress Relieving Strategy to Nanotoxicology- Juniper Publishers

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Juniper Publishers- Journal of Cell Science Abstract Nanoparticles are exponentially being used for their enormous sectors of applications. Human exposure and the ensuing distress is thus an inevitability. Despite the scores of ongoing research, there is still a lack of comprehensive revival strategies for treatment of the affected tissue. There is also no single standard procedure of prognosis, as the implications of toxicity are varied, and their symptoms also vary with each individual case of affliction. There is thus always a need for discovery of new targets and routes of treatment for better efficacy at therapy. We have discovered that encouraging cell migration could be one of these solutions. Keywords: Nanoparticles; EMT; Stress; Recovery Abbreviations: NP: Nano Particle; Me Ox: Metal Oxide; EMT: Epithelial to Mesenchymal Transition Introduction Nanotoxicology is a growing concern, particularly stress incited by expo...
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