Gut Microbes as a Novel Prognostic and Therapeutic Model in Cancer-Juniper Publishers


Gut Microbes as a Novel Prognostic and Therapeutic Model inCancer by Nahla AM Hamed in Juniper Publishers in International Journal of CellScience & Molecular Biology


In addition to its association with an expanding list of chronic disorders, commensal microbiota is major player affecting the outcome of carcinogenesis, tumor progression, cancer comorbidities, and response to therapy. Previous studies showed that microbial disturbance by antibiotic exposure severely compromised the efficacy of cyclophosphamide and platinum-based chemotherapeutics. Many of the critical clinical outcomes after allo-HSCT, including overall survival, infections and GVHD are closely linked to changes in the intestinal flora.

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