Biomolecular Interaction and Photohemolytic Effect of Gold Nanoparticles- Juniper Publishers
The interaction between colloidal gold nano particles 
with bovine serum albumin, hemoglobin and Deoxy Ribo Nucleic acid were 
studied by spectroscopy. The conjugation of proteins with NPs not only 
affords stabilization of the system but, more importantly, also 
introduces biocompatible functionalities into nano particles for further 
biological interactions. The surface modifications of gold nano particles
 to provide stable bimolecular functionalized NPs in biomedical 
applications have been reported. Next, photo hemolytic activity of gold 
nanoparticles and light photons in hematocrit were studied. Photo induced hemolysis is a colloidal-osmotic 
process due to loss of selective permeability of the photo damaged 
membrane leads to indiscriminate entrance of solute molecules, swelling 
and eventual membrane rupture. 30 nm gold nanoparticles were synthesized
 by reduction technique using trisodium citrate and the size was 
confirmed by Transmission electron Microscopy and UV-Visible absorption 
spectroscopy.
https://juniperpublishers.com/ijcsmb/IJCSMB.MS.ID.555567.php
https://juniperpublishers.com/ijcsmb/IJCSMB.MS.ID.555567.php
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